KINETIC PROFILING AN ABUNDANTLY EXPRESSED PLANARIAN SEROTONERGIC GPCR IDENTIFIES BROMOCRIPTINE AS A PERDURANT ANTAGONIST

Kinetic profiling an abundantly expressed planarian serotonergic GPCR identifies bromocriptine as a perdurant antagonist

Accessories:Car The diversity and uniqueness of flatworm G protein coupled receptors (GPCRs) provides impetus for identifying ligands useful as tools for studying flatworm biology, or as therapeutics for treating diseases caused by parasitic flatworm infections.To catalyse this discovery process, technologies optimized for mammalian GPCR high throu

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MicroRNA-650 was a prognostic factor in human lung adenocarcinoma and confers the docetaxel chemoresistance of lung adenocarcinoma cells via regulating Bcl-2/Bax expression.

Increasing evidence shows that dysregulation of microRNAs (miRNAs) is involved in malignant transformation.We investigated the clinical significance of miR-650 and its involvement in chemoresistance to docetaxel.Our results showed that the relative expression level of miR-650 was significantly higher in LAD tissues than in corresponding nontumor ti

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Socio-Economic Profile, Challenges, and Emergency Assistance during the COVID-19 Lockdown: A Case Study on Household Industry Workers in Murshidabad District, India

MSM COVID-19 lockdown causes severe socio-economic vulnerability among the household industry workers (HIWs) in India.In this study, the socio-economic profile, challenges, and emergency assistance received by these workers during the COVID-19 lockdown were described.A field survey was conducted among HIWs in Murshidabad District, India, from June

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Non-Dimensional Groups, Film Thickness Equations and Correction Factors for Elastohydrodynamic Lubrication: A Review

Apart from complex numerical models to predict the tribological behavior of elastohydrodynamically lubricated contacts, non-dimensional similarity groups and analytically solvable proximity equations can be used to estimate integral fluid film parameters.Based upon the pioneering work presented by Dowson and Higginson as well as PRO-ADD Blok and Mo

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